Obesity Abstracts

Background: Resting energy expenditure (REE) and diet induced thermogenesis (DIT) are known to influence long term maintenance of weight loss following bariatric surgery. Although it is known that fat free mass (FFM) contributes to REE to a greater extent than fat mass (FM), there has been relatively little work looking at the REE:FFM ratio and its overall effect on and relationship to weight loss.Aim: To assess weight loss, REE and REE:MMT ratio in pati...

Background: Hyperglucagonaemia is one of the key players in the pathophysiology of type 2 diabetes. Roux-en-Y Gastric Bypass (RYGB) is currently a highly effective treatment for weight loss and diabetes remission. However, the role of glucagon in the above effects is unclear.Aim: To characterise the behaviour of proglucagon-derived peptides (glucagon, glucagon-like peptide-1, oxyntomodulin, glicentin) after RYGB surgery.Subjects an...

Background: Roux-en-Y Gastric Bypass (RYGB) and Sleeve Gastrectomy are two widely used bariatric procedures. Longitudinal data have shown similar efficacy in terms of sustained weight loss and diabetes remission in obese patients with type 2 diabetes. Altered glucose dynamics with increased glycaemic variability and the occurrence of hypoglycaemia are common post-bariatric surgery. Aim: To compare the glycaemic variability and incidence of hypoglycaemia ...